Using probiotics to help treat depression in teenagers

Probiotic Administration for Adolescent Depression

NIH-funded research University of California, San Francisco · NIH-10930815

This study is looking at whether a special blend of probiotics called Visbiome® can help improve depression symptoms in teens aged 12 to 20 by exploring how it affects their brain and gut health, especially for those who haven't found relief with regular treatments.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10930815 on NIH RePORTER

What this research studies

This research investigates the potential of probiotics, specifically a multi-strain formulation called Visbiome®, to improve symptoms of depression in adolescents aged 12 to 20. The study aims to understand how these probiotics can affect brain connectivity and the gut microbiome, which are believed to be linked to mental health. By monitoring changes in brain function and gut bacteria, the research seeks to identify new, effective treatments for adolescent depression, especially for those who have not responded well to traditional therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who have been diagnosed with a clinical depressive disorder.

Not a fit: Patients outside the age range of 12 to 20 or those without a clinical diagnosis of depression may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a novel, non-invasive treatment option for adolescents suffering from depression.

How similar studies have performed: While the use of probiotics for mental health is an emerging field, preliminary studies suggest potential benefits, indicating that this approach is promising but still requires further investigation.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.