Using prebiotics to improve cognitive function in people with schizophrenia
Prebiotic Treatment in People with Schizophrenia
['FUNDING_OTHER'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-10878800
This study is looking at whether a special treatment that helps good bacteria in the gut can improve thinking and memory in people with schizophrenia, and it’s designed for those who want to explore new ways to boost their brain health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MARYLAND BALTIMORE (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10878800 on ClinicalTrials.gov |
What this research studies
This research investigates the potential of prebiotic treatment to enhance cognitive function in individuals diagnosed with schizophrenia. It focuses on the role of gut microbiota and its impact on brain health, particularly through the production of short-chain fatty acids like butyrate. By promoting the growth of beneficial gut bacteria, the study aims to address cognitive impairments that are often resistant to traditional treatments. Participants will be involved in a double-blind trial to assess the effectiveness of this novel approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with schizophrenia who experience cognitive impairments.
Not a fit: Patients who do not have a diagnosis of schizophrenia or those with cognitive impairments due to other conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary interventions that significantly improve cognitive function and overall quality of life for individuals with schizophrenia.
How similar studies have performed: While the approach of using prebiotics for cognitive enhancement in schizophrenia is relatively novel, there is emerging evidence suggesting that gut microbiota can influence brain function, indicating potential for success.
Where this research is happening
BALTIMORE, UNITED STATES
- UNIVERSITY OF MARYLAND BALTIMORE — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BUCHANAN, ROBERT W — UNIVERSITY OF MARYLAND BALTIMORE
- Study coordinator: BUCHANAN, ROBERT W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.