Using positive airway pressure to treat sleep apnea in children with Down syndrome
Positive Airway Pressure For The Treatment Of The Obstructive Sleep Apnea Syndrome In Children With Down Syndrome
This study is looking at how well a special breathing machine called PAP therapy helps kids with Down syndrome and sleep apnea, by comparing a six-month hands-on support program to regular care, to see which helps them stick with the treatment better and feel better overall.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10912150 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of positive airway pressure (PAP) therapy in treating obstructive sleep apnea (OSAS) in children with Down syndrome. It aims to compare a six-month intensive behavioral intervention to standard clinical care to improve adherence to PAP therapy. The study will involve children aged 6 to 17.9 years who have been referred for PAP initiation due to persistent OSAS after adenotonsillectomy. Participants will undergo evaluations to assess improvements in quality of life, behavior, and other neurobehavioral symptoms associated with OSAS.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 6 to 17.9 years with Down syndrome who have been diagnosed with obstructive sleep apnea and are referred for positive airway pressure therapy.
Not a fit: Patients who do not have Down syndrome or those who do not have obstructive sleep apnea may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life and behavioral outcomes for children with Down syndrome suffering from obstructive sleep apnea.
How similar studies have performed: Previous research has shown that positive airway pressure therapy is effective in treating obstructive sleep apnea, but this specific approach in children with Down syndrome is relatively novel.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Tapia, Ignacio Esteban — University of Miami School of Medicine
- Study coordinator: Tapia, Ignacio Esteban
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.