Using positive airway pressure to treat sleep apnea in children with Down syndrome
Positive Airway Pressure For The Treatment Of The Obstructive Sleep Apnea Syndrome In Children With Down Syndrome
This study is looking at how well positive airway pressure (PAP) therapy works for kids with Down syndrome who have trouble breathing at night due to sleep apnea, and it aims to understand how this treatment can help improve their daily lives and behavior.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10911685 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of positive airway pressure (PAP) therapy for treating obstructive sleep apnea syndrome (OSAS) in children with Down syndrome. Given that children with Down syndrome often experience persistent OSAS even after standard treatments like adenotonsillectomy, this study aims to explore how PAP can improve their quality of life and neurobehavioral symptoms. Families of affected children will be interviewed to gather insights on their experiences and outcomes with PAP therapy. The findings will help inform a larger randomized controlled trial to assess the benefits of PAP in this specific population.
Who could benefit from this research
Good fit: Ideal candidates for this research are children with Down syndrome who are diagnosed with obstructive sleep apnea and may benefit from positive airway pressure therapy.
Not a fit: Patients who do not have Down syndrome or those without obstructive sleep apnea are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life and behavioral outcomes for children with Down syndrome suffering from obstructive sleep apnea.
How similar studies have performed: While positive airway pressure therapy has been effective in treating obstructive sleep apnea in general, its specific application and outcomes in children with Down syndrome have not been extensively studied, making this research a novel approach.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Tapia, Ignacio Esteban — University of Miami School of Medicine
- Study coordinator: Tapia, Ignacio Esteban
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.