Using pomalidomide to treat bleeding in patients with hereditary hemorrhagic telangiectasia.
2/2 Pomalidomide for Bleeding in Patients with Hereditary Hemorrhagic Telangiectasia (HHT) Bleeding Data Coordinating Center
This study is looking at how well the medication pomalidomide can help reduce bleeding for people with hereditary hemorrhagic telangiectasia (HHT), a condition that causes frequent bleeding due to abnormal blood vessels.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project ID | NIH-10581610 on NIH RePORTER |
What this research studies
This research investigates the use of pomalidomide, a medication similar to thalidomide, to help manage bleeding in patients with hereditary hemorrhagic telangiectasia (HHT). HHT is a genetic disorder that causes abnormal blood vessel formations leading to frequent bleeding episodes, particularly from the nose and gastrointestinal tract. The study aims to evaluate the effectiveness of pomalidomide in reducing these bleeding events and improving overall patient health. By coordinating data from various patients, the research seeks to establish a more effective treatment protocol for HHT.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with hereditary hemorrhagic telangiectasia who experience frequent bleeding episodes.
Not a fit: Patients without a diagnosis of hereditary hemorrhagic telangiectasia or those who do not experience significant bleeding may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new treatment option for patients suffering from severe bleeding due to HHT.
How similar studies have performed: Previous studies have shown promise with thalidomide for HHT, suggesting that similar approaches with pomalidomide may also be effective.
Where this research is happening
Research Triangle Park, United States
- Research Triangle Institute — Research Triangle Park, United States (Active)
Researchers
- Principal investigator: Thomas, Sonia M — Research Triangle Institute
- Study coordinator: Thomas, Sonia M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.