Using plasma-generated radicals to analyze protein structures
Plasma-Generated Hydroxyl Radicals for Analysis of Three-Dimensional Structures in Protein Therapeutics
['FUNDING_SBIR_2'] · IMMUTO SCIENTIFIC, INC. · NIH-10892250
This study is working on a new machine that can quickly look at the shapes of important protein-based treatments like antibodies and vaccines, helping to make sure they are safe and effective for patients.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | IMMUTO SCIENTIFIC, INC. (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-10892250 on ClinicalTrials.gov |
What this research studies
This research focuses on developing an automated benchtop instrument that can quickly and efficiently analyze the three-dimensional structures of protein-based biotherapeutics, such as antibodies and vaccines. By utilizing plasma-generated hydroxyl radicals, the instrument aims to provide high-throughput structural characterization, which is essential for ensuring the safety and efficacy of these treatments. The study emphasizes the importance of understanding the higher order structures of proteins, as they directly influence the function and stability of therapeutic agents. This innovative approach could significantly reduce the time required for structural analysis compared to traditional methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that may be treated with protein biotherapeutics, including cancers, autoimmune diseases, and infectious diseases like COVID-19.
Not a fit: Patients who do not require protein-based therapies or those with conditions unrelated to the focus of this research may not benefit.
Why it matters
Potential benefit: If successful, this research could lead to faster and more reliable development of protein-based therapies, improving treatment options for various diseases.
How similar studies have performed: Other research has shown success in utilizing advanced structural analysis techniques for biotherapeutics, indicating that this approach has potential for significant advancements.
Where this research is happening
MADISON, UNITED STATES
- IMMUTO SCIENTIFIC, INC. — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHOUDHURY, FARAZ — IMMUTO SCIENTIFIC, INC.
- Study coordinator: CHOUDHURY, FARAZ
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.