Using plant-based supplements to reduce stress-related immune responses
Suppression of Immune Signatures of Stress by Polyphenols Supplements
This study is looking at how a special plant-based supplement might help your brain stay healthy and feel better during stressful times by supporting your immune system and reducing inflammation.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10886089 on NIH RePORTER |
What this research studies
This research investigates how a specific botanical supplement, rich in polyphenols, can help protect against the negative effects of stress on the brain and behavior. It focuses on how these supplements interact with immune cells and brain structures to maintain healthy brain function and prevent depressive symptoms. By studying the effects of these supplements on inflammation and blood-brain barrier integrity, the research aims to provide insights into new ways to enhance mental resilience in individuals facing stress.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing high levels of stress or those at risk for depression.
Not a fit: Patients who are not experiencing stress or depressive symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary supplements that help individuals better cope with stress and reduce the risk of depression.
How similar studies have performed: Previous research has shown promising results with similar botanical supplements in reducing inflammation and improving mental health outcomes.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Russo, Scott James — Icahn School of Medicine at Mount Sinai
- Study coordinator: Russo, Scott James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.