Using Pimavanserin to improve sleep in veterans with PTSD
Pimavanserin for Insomnia in Veterans with Post-traumatic Stress Disorder
This study is looking at how the medication Pimavanserin, usually used for Parkinson's disease, can help veterans with PTSD sleep better and feel less anxious, and it’s being led by Dr. Melissa Beth Jones.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michael E Debakey VA Medical Center NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10975958 on NIH RePORTER |
What this research studies
This research investigates the effects of Pimavanserin, a medication typically used for Parkinson's disease psychosis, on insomnia in veterans suffering from post-traumatic stress disorder (PTSD). The study aims to assess how this medication can help improve sleep quality and reduce symptoms associated with PTSD. Patients will be monitored through various assessments, including actigraphy, to evaluate sleep patterns and overall mental health. The research is led by Dr. Melissa Beth Jones, who is focused on developing effective treatments for neuropsychiatric conditions in veterans.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans aged 21 and older who experience insomnia related to PTSD.
Not a fit: Patients who do not have PTSD or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved sleep and overall mental health for veterans suffering from PTSD.
How similar studies have performed: Previous research has shown promising results using similar medications for sleep disturbances in PTSD, indicating potential for success in this approach.
Where this research is happening
Houston, United States
- Michael E Debakey VA Medical Center — Houston, United States (Active)
Researchers
- Principal investigator: Jones, Melissa Beth — Michael E Debakey VA Medical Center
- Study coordinator: Jones, Melissa Beth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.