Using photoacoustic imaging to improve diagnosis of intestinal health in premature infants

Photoacoustic Imaging for Biophysical Physiological Indicators of Neonatal Intestinal Health and Necrotizing Enterocolitis

NIH-funded research Wake Forest University Health Sciences · NIH-11060070

This study is testing a new, gentle imaging method to help doctors spot a serious intestinal disease called necrotizing enterocolitis in premature babies, so they can catch it early and provide better care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-11060070 on NIH RePORTER

What this research studies

This research focuses on developing a new imaging technique called photoacoustic imaging (PAI) to help diagnose necrotizing enterocolitis (NEC) in premature infants. NEC is a serious intestinal disease that can be life-threatening, and early diagnosis is crucial for effective treatment. The study aims to use PAI to non-invasively detect changes in the intestines of infants, allowing for better monitoring and management of this condition. By characterizing the blood flow and motility in the intestines, the research hopes to provide healthcare providers with more accurate diagnostic tools.

Who could benefit from this research

Good fit: Ideal candidates for this research are premature infants who are at high risk for developing necrotizing enterocolitis.

Not a fit: Patients who are not premature or do not have risk factors for necrotizing enterocolitis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of NEC, potentially saving lives and improving outcomes for premature infants.

How similar studies have performed: While photoacoustic imaging is a novel approach in this context, similar imaging techniques have shown promise in other medical applications, indicating potential for success.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.