Using peptides from heart tissue to improve healing after heart attacks
Peptides derived from soluble extracellular matrix for promoting improved healing following myocardial infarction
This study is looking at special proteins from heart tissue that could help improve healing after a heart attack, aiming to find better treatments to help patients recover more effectively.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts University Medford NIH-funded |
| Lab location | 1 site (Boston, UNITED STATES) |
| Project ID | NIH-10705333 on NIH RePORTER |
What this research studies
This research investigates how specific peptides derived from the extracellular matrix of heart tissue can enhance healing after a myocardial infarction (heart attack). The approach focuses on identifying and characterizing these peptides to develop a more consistent and effective treatment option. By utilizing acellular biomaterials, the study aims to alter the heart's remodeling response, potentially leading to better recovery outcomes for patients. The research builds on previous findings that suggest younger heart tissue may provide more regenerative properties.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced a myocardial infarction.
Not a fit: Patients who have not had a myocardial infarction or those with advanced heart failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved healing and recovery for patients who have suffered a heart attack, potentially reducing the risk of heart failure.
How similar studies have performed: Previous studies have shown promise in using acellular biomaterials for heart repair, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
Boston, UNITED STATES
- Tufts University Medford — Boston, United States (Active)
Researchers
- Principal investigator: Black Iii, Lauren D. — Tufts University Medford
- Study coordinator: Black Iii, Lauren D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.