Using peer support to help people with substance use improve HIV prevention and treatment with long-acting injections

Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH).”

['FUNDING_R01'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-11158975

This project explores how peer support can help people who use drugs better manage their HIV prevention or treatment with long-acting injectable medications.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MARYLAND BALTIMORE (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-11158975 on ClinicalTrials.gov

What this research studies

Substance use can make it harder to prevent HIV and to stick with HIV treatment, even with new long-acting injectable medications (PrEP for prevention, ART for treatment). This project is testing a program called "Peer Activate," where trained peers help individuals develop problem-solving skills. The program also encourages engaging in rewarding, substance-free activities and structured daily routines to promote consistent medication use. The goal is to ensure these important long-acting injectable medications work as effectively as possible for people who also use drugs.

Who could benefit from this research

Good fit: Ideal candidates are people who use drugs and are receiving or considering long-acting injectable PrEP for HIV prevention or ART for HIV treatment.

Not a fit: Patients who do not use drugs or are not receiving long-acting injectable PrEP/ART may not directly benefit from this specific intervention.

Why it matters

Potential benefit: If successful, this approach could help people who use drugs better prevent HIV or manage their HIV infection, leading to improved health outcomes.

How similar studies have performed: The research builds on prior studies showing the feasibility of engaging patients and the promise of the Peer Activate intervention in other contexts, but it has not yet been tested with long-acting injectable PrEP/ART.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.