Using oxygen to help babies during labor
Maternal oxygen supplementation for Intrauterine Resuscitation: a Multicenter Randomized Trial
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-10915025
This study is looking at whether giving extra oxygen to moms during labor can help keep their babies healthy when there's a concern about low oxygen levels, and it’s for pregnant women who are being closely monitored during delivery.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10915025 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of maternal oxygen supplementation during labor on fetal health, particularly in cases of suspected fetal hypoxia. The study involves a multicenter randomized trial where pregnant women receiving continuous electronic fetal monitoring will be given either supplemental oxygen or room air. The goal is to determine if oxygen supplementation significantly improves outcomes for the fetus, such as reducing the risk of acidemia and neonatal complications. By comparing these two approaches, the research aims to provide evidence-based guidelines for clinical practice.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women undergoing labor who are monitored for fetal heart rate and may be at risk for fetal hypoxia.
Not a fit: Patients who are not in labor or those with pre-existing conditions that contraindicate oxygen supplementation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved fetal health outcomes during labor and delivery.
How similar studies have performed: Previous studies have shown that room air is noninferior to oxygen in terms of fetal health outcomes, indicating that this research builds on existing findings.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RAGHURAMAN, NANDINI — WASHINGTON UNIVERSITY
- Study coordinator: RAGHURAMAN, NANDINI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.