NIH-funded research Fellowship grant

Using omega-3 fatty acids to reduce lung inflammation caused by obesity

Official title: Reducing Pulmonary Inflammation in Obesity with Docosahexaenoic Acid

Funded at Univ of North Carolina Chapel Hill · NIH-10997998 · Data updated 2026-11-12

This study is looking at how adding more DHA, a type of omega-3 fatty acid found in fish, to the diet might help reduce lung inflammation in people who are obese, with the goal of finding new ways to improve lung health.

More Obesity research and trials

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startSeptember 13, 2024
Project endMarch 13, 2027
Funding year2024
Award (this year)$40,583
NIH project number1F31HL176155-01
Project IDNIH-10997998 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults over 21 years old who are experiencing lung inflammation related to obesity.

Less likely to help

Patients who are not obese or do not have lung inflammation may not benefit from this research.

What this research studies

This research investigates how increasing dietary docosahexaenoic acid (DHA), an omega-3 fatty acid, can help reduce pulmonary inflammation in individuals with obesity. The study focuses on understanding how DHA interacts with alveolar macrophages, which play a crucial role in lung health and inflammation. By examining the mechanisms through which DHA alters inflammatory responses, the research aims to establish a new therapeutic approach for managing lung diseases exacerbated by obesity.

Why it matters

Potential benefit: If successful, this research could lead to new dietary recommendations or treatments that significantly improve lung health in obese patients.

How similar studies have gone: Previous research has shown promising results in using omega-3 fatty acids for reducing inflammation, suggesting that this approach may be effective.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Virk, Rafia — Univ of North Carolina Chapel Hill
  • Study coordinator: Virk, Rafia

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.