Using omega-3 fatty acids to reduce lung inflammation caused by obesity

Reducing Pulmonary Inflammation in Obesity with Docosahexaenoic Acid

['FUNDING_FELLOWSHIP'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-10997998

This study is looking at how adding more DHA, a type of omega-3 fatty acid found in fish, to the diet might help reduce lung inflammation in people who are obese, with the goal of finding new ways to improve lung health.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorUNIV OF NORTH CAROLINA CHAPEL HILL (nih funded)
Locations1 site (CHAPEL HILL, UNITED STATES)
Trial IDNIH-10997998 on ClinicalTrials.gov

What this research studies

This research investigates how increasing dietary docosahexaenoic acid (DHA), an omega-3 fatty acid, can help reduce pulmonary inflammation in individuals with obesity. The study focuses on understanding how DHA interacts with alveolar macrophages, which play a crucial role in lung health and inflammation. By examining the mechanisms through which DHA alters inflammatory responses, the research aims to establish a new therapeutic approach for managing lung diseases exacerbated by obesity.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing lung inflammation related to obesity.

Not a fit: Patients who are not obese or do not have lung inflammation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new dietary recommendations or treatments that significantly improve lung health in obese patients.

How similar studies have performed: Previous research has shown promising results in using omega-3 fatty acids for reducing inflammation, suggesting that this approach may be effective.

Where this research is happening

CHAPEL HILL, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acute Lung Injury, Acute Pulmonary Injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.