Using omega-3 fatty acids to prevent brain injury from head impacts in soccer players
Official title: A mechanistic clinical trial of omega-3 fatty acids to prevent subconcussive neural injury
Funded at Trustees of Indiana University · NIH-11075917 · Data updated 2026-11-12
This study is looking at whether taking omega-3 supplements can help protect soccer players' brains from injuries caused by small hits to the head, and it’s for athletes who want to stay sharp and healthy while playing.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Trustees of Indiana University NIH-funded |
| Lab location | 1 site (Bloomington, United States) |
| Project start | June 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $591,446 |
| NIH project number | 5R01NS137276-02 |
| Project ID | NIH-11075917 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are soccer players aged 21 and younger who frequently experience head impacts during play.
✕Less likely to help
Patients who do not play contact sports or have pre-existing neurological conditions may not benefit from this research.
What this research studies
This research investigates the potential of omega-3 fatty acids, particularly DHA and EPA, to prevent brain injuries caused by subconcussive head impacts, which are common in soccer. The study will involve a randomized clinical trial where participants will receive omega-3 supplements to assess their effectiveness in reducing biomarkers of neural injury and maintaining cognitive function. By focusing on the physiological changes that occur after head impacts, the research aims to provide a preventive strategy for athletes at risk of long-term neurological issues. Participants will be monitored for changes in blood biomarkers and cognitive performance over time.
Why it matters
Potential benefit: If successful, this research could provide a preventive treatment to protect athletes from long-term brain damage associated with repeated head impacts.
How similar studies have gone: Previous studies have shown promising results in using omega-3 fatty acids to mitigate brain injury effects, suggesting this approach may be effective.
Where this research is happening
-
Trustees of Indiana University
Bloomington, United States Active
Researchers
- Principal investigator: Kawata, Keisuke — Trustees of Indiana University
- Study coordinator: Kawata, Keisuke
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.