Using nutrition to improve vaccine effectiveness
Harnessing nutrition to enhance vaccine responses
['FUNDING_R01'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11048545
This study is looking at how eating fewer calories might help your body respond better to vaccines, especially for new viruses like COVID-19, and it hopes to find ways to improve vaccine effectiveness for everyone.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11048545 on ClinicalTrials.gov |
What this research studies
This research investigates how nutritional strategies, specifically caloric restriction, can enhance the immune response to vaccines against emerging pathogens like SARS-CoV2 and others. By studying the molecular mechanisms and interactions involved, the research aims to uncover how caloric restriction can boost immunological memory and improve pathogen control. The findings could lead to new therapies that mimic the immune-enhancing effects of caloric restriction, potentially benefiting vaccine responses in humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are receiving vaccines for emerging infectious diseases and are interested in nutritional interventions.
Not a fit: Patients who are not receiving vaccines or those with conditions that prevent them from undergoing caloric restriction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccine responses and better protection against infectious diseases for patients.
How similar studies have performed: Previous studies have shown that caloric restriction can significantly enhance immune responses in animal models, indicating potential for success in human applications.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: COLLINS, NICHOLAS — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: COLLINS, NICHOLAS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.