Using noninvasive nerve stimulation and smartphone apps to help prevent suicide in vulnerable teens

Leveraging Noninvasive Transcutaneous Vagus Nerve Stimulation and Smartphone Technology to Reduce Suicidal Behaviors and Suicide Among Highly Vulnerable Adolescents

['FUNDING_R01'] · UNIVERSITY OF NOTRE DAME · NIH-10910071

This study is exploring a new way to help teens aged 12 to 20 who might be struggling with feelings of sadness or loneliness by using a special device and a smartphone app that connects them with friends for support, making it easier for them to feel better and stay safe.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF NOTRE DAME (nih funded)
Locations1 site (NOTRE DAME, UNITED STATES)
Trial IDNIH-10910071 on ClinicalTrials.gov

What this research studies

This research investigates innovative ways to reduce suicidal behaviors among adolescents aged 12 to 20 by combining noninvasive transcutaneous vagus nerve stimulation (tVNS) with a peer-support smartphone application. The approach aims to address emotional dysregulation and social isolation, which are significant factors in adolescent suicide risk. By utilizing technology that is accessible and preferred by teens, the study seeks to provide effective primary prevention strategies that can be delivered without the need for extensive mental health resources. Participants will engage with these interventions in a way that is convenient and familiar to them, potentially leading to better outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who are at risk for suicidal behaviors, particularly those who may not have access to traditional mental health services.

Not a fit: Patients who are not within the age range of 12 to 20 or those who do not exhibit suicidal behaviors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly lower suicide rates among vulnerable adolescents by providing accessible and effective mental health interventions.

How similar studies have performed: While the combination of tVNS and smartphone technology is a novel approach, previous studies have shown promise in using similar noninvasive techniques for mental health interventions.

Where this research is happening

NOTRE DAME, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.