NIH-funded research NIH-funded research

Using non-invasive vagal nerve stimulation to help Veterans with alcohol use disorder

Official title: Non-invasive vagal nerve stimulation as novel treatment to improve functionaloutcomes in Veterans with alcohol use disorder

Funded at VA San Diego Healthcare System · NIH-10992575 · Data updated 2026-11-12

This study is looking at a gentle treatment called non-invasive vagal nerve stimulation to help Veterans who are trying to overcome alcohol use disorder, with the hope of making it easier for them to manage withdrawal symptoms and stay on track in their recovery.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA San Diego Healthcare System
NIH-funded
Lab location1 site (San Diego, United States)
Project startOctober 1, 2024
Project endSeptember 30, 2029
Funding year2025
NIH project number1IK2RX004777-01A2
Project IDNIH-10992575 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are Veterans diagnosed with alcohol use disorder who are seeking treatment and support for their condition.

Less likely to help

Patients who are not Veterans or those who do not have alcohol use disorder may not benefit from this research.

What this research studies

This research investigates the use of non-invasive vagal nerve stimulation (nVNS) as a potential treatment for alcohol use disorder (AUD) in Veterans. The study aims to address the high relapse rates associated with AUD by targeting the vagus nerve, which plays a crucial role in regulating the body's physiological balance. By stimulating this nerve, the researchers hope to alleviate withdrawal symptoms and improve overall functional outcomes for participants. The approach is designed to be safe and non-invasive, making it accessible for Veterans seeking help with their alcohol use.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for Veterans struggling with alcohol use disorder, potentially reducing relapse rates and improving quality of life.

How similar studies have gone: Previous research has shown that non-invasive vagal nerve stimulation can be effective in alleviating symptoms related to other substance use disorders, suggesting potential for success in this novel application.

Where this research is happening

  • VA San Diego Healthcare System
    San Diego, United States
    Active

Researchers

  • Principal investigator: Klaming, Ruth — VA San Diego Healthcare System
  • Study coordinator: Klaming, Ruth

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.