Using non-invasive nerve stimulation to help patients with opioid use disorders
Non-Invasive Vagal Nerve Stimulation in Patients with Opioid Use Disorders
This study is looking at a gentle way to help people who are going through withdrawal from opioids feel better and have fewer cravings before they start taking naltrexone, a medication that helps with addiction.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11088252 on NIH RePORTER |
What this research studies
This research investigates a non-invasive method of stimulating the vagus nerve to assist patients undergoing withdrawal from opioids before starting treatment with naltrexone, an opioid antagonist. The approach aims to reduce withdrawal symptoms and cravings by modulating the nervous system's response to opioids. By enhancing brain function and reducing inflammation, the study seeks to improve the transition to long-term treatment for opioid use disorders. Patients will be monitored for their response to this neuromodulation technique during the critical withdrawal phase.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorders who are seeking treatment and are in need of support during the withdrawal phase.
Not a fit: Patients who are not experiencing opioid withdrawal or those who are not interested in pharmacological treatment options may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer and more acceptable way for patients to manage withdrawal symptoms and reduce the risk of relapse during treatment for opioid use disorders.
How similar studies have performed: Previous research has shown promise in using neuromodulation techniques for addiction treatment, indicating potential for success in this novel approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Bremner, James Douglas — Emory University
- Study coordinator: Bremner, James Douglas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.