Using nitrite supplements to help improve function and reduce fatigue in long COVID patients
Nitrite Supplementation to Mitigate Fatigability and Increase Function in Long COVID Patients
This study is looking at whether drinking beetroot juice, which is high in nitrites, can help veterans with long COVID feel stronger and less tired, by comparing it to a placebo, to see if it improves their physical performance and overall well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11229567 on NIH RePORTER |
What this research studies
This research investigates the effects of nitrite supplementation on veterans suffering from long COVID, a condition that often leads to decreased physical function and quality of life. The study will compare the effects of nitrate-rich beetroot juice to a placebo on improving muscle function and reducing fatigue. Participants will be monitored for changes in their physical performance, specifically looking at how nitrite levels in the body correlate with improvements in cardiorespiratory fitness and perceived exertion during exercise. The goal is to determine if this dietary intervention can enhance recovery and overall well-being in affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans over the age of 21 who are experiencing long COVID symptoms, particularly those with muscle fatigue and decreased physical function.
Not a fit: Patients who are not veterans or those who do not have long COVID symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new dietary approach to alleviate symptoms of long COVID and improve the quality of life for patients.
How similar studies have performed: Previous research has shown promising results with nitrite supplementation in improving muscle function and exercise capacity, suggesting potential for success in this new application.
Where this research is happening
Pittsburgh, United States
- Veterans Health Administration — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Forman, Daniel E. — Veterans Health Administration
- Study coordinator: Forman, Daniel E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.