Using new nanoparticles to improve imaging of implantable biomaterials
Evaluation of tantalum oxide nanoparticles for in vivo X-ray computed tomography evaluation of implantable biomaterials
['FUNDING_R01'] · MICHIGAN STATE UNIVERSITY · NIH-10735797
This study is testing a new type of imaging tool that uses tiny particles to help doctors see how well special implants, like those used to help heal skin and bone, are working inside your body over time.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MICHIGAN STATE UNIVERSITY (nih funded) |
| Locations | 1 site (EAST LANSING, UNITED STATES) |
| Trial ID | NIH-10735797 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a novel contrast agent made from tantalum oxide nanoparticles to enhance X-ray computed tomography (CT) imaging for monitoring implantable biomaterials in patients. The goal is to create a safer and more effective way to visualize tissue engineered scaffolds (TES) that help regenerate various tissues, such as skin and bone. By using this new imaging method, researchers aim to accurately measure how these biomaterials degrade over time within the body, providing critical information about their performance and safety. This approach could lead to better clinical monitoring of these implants post-surgery, ensuring they function as intended.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing procedures involving implantable biomaterials for tissue regeneration.
Not a fit: Patients who do not require implantable biomaterials or are not undergoing related surgical procedures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved safety and effectiveness of implantable biomaterials used in regenerative medicine.
How similar studies have performed: Previous research has shown promise in using similar imaging techniques for monitoring biomaterials, but this specific approach with tantalum oxide nanoparticles is novel.
Where this research is happening
EAST LANSING, UNITED STATES
- MICHIGAN STATE UNIVERSITY — EAST LANSING, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHAPIRO, ERIK — MICHIGAN STATE UNIVERSITY
- Study coordinator: SHAPIRO, ERIK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.