Using new materials to treat abnormal blood vessel connections
Biomaterials for embolization and ablation of arterio-venous malformations
This study is working on new materials to help treat arteriovenous malformations (AVMs) by creating special agents that can safely block the abnormal blood vessels, especially for patients who can’t have regular surgery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project ID | NIH-10881989 on NIH RePORTER |
What this research studies
This research focuses on developing innovative biomaterials for the treatment of arteriovenous malformations (AVMs), which are abnormal connections between arteries and veins that can lead to serious complications like bleeding. The approach involves creating new embolic agents that can be used to block these abnormal vessels, particularly in patients who are not candidates for traditional surgery. By utilizing advanced biomedical engineering techniques, the research aims to improve the safety and effectiveness of AVM treatments, especially for those experiencing acute bleeding or with high surgical risks.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with arteriovenous malformations who are not suitable for surgical intervention due to their health conditions or the location of the AVM.
Not a fit: Patients with AVMs that are easily accessible for surgical resection or those who do not have significant health risks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide safer and more effective treatment options for patients with arteriovenous malformations, potentially reducing the risk of life-threatening bleeding.
How similar studies have performed: Previous research has shown promise in using novel biomaterials for vascular treatments, indicating potential success for this approach.
Where this research is happening
Scottsdale, United States
- Mayo Clinic Arizona — Scottsdale, United States (Active)
Researchers
- Principal investigator: Oklu, Rahmi — Mayo Clinic Arizona
- Study coordinator: Oklu, Rahmi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.