Using neurostimulation to help veterans with severe PTSD

Responsive Neurostimulation for Post-Traumatic Stress Disorder

NIH-funded research University of California Los Angeles · NIH-10668215

This study is looking at a new way to help veterans with severe PTSD by using a device that monitors brain activity and helps reduce fear, with the goal of finding a better treatment for their symptoms.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10668215 on NIH RePORTER

What this research studies

This research investigates the use of Responsive Neurostimulation (RNS) to help veterans suffering from severe treatment-resistant post-traumatic stress disorder (PTSD). The approach involves chronic recording of brain activity from the amygdala, which is crucial for processing fear and anxiety, while applying neuromodulation techniques to promote fear extinction. By understanding how the brain responds to trauma reminders, the study aims to develop a more effective treatment for PTSD. Participants will be closely monitored to assess the impact of this innovative therapy on their symptoms.

Who could benefit from this research

Good fit: Ideal candidates for this research are veterans diagnosed with severe treatment-resistant PTSD.

Not a fit: Patients who do not have PTSD or those whose symptoms are well-managed with existing treatments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new treatment option for veterans with severe PTSD who have not responded to traditional therapies.

How similar studies have performed: Previous research has shown promising results with neuromodulation techniques in treating PTSD, indicating potential for success in this approach.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.