Using nerve stimulation to influence brain reward systems related to appetite.
Peripheral nerve stimulation for control of the mesolimbic dopamine system
['FUNDING_R21'] · UNIVERSITY OF TEXAS DALLAS · NIH-10653224
This study is looking at how gently stimulating a specific nerve in your neck might help control your appetite and improve your eating habits, especially for people dealing with eating issues or certain brain conditions.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS DALLAS (nih funded) |
| Locations | 1 site (RICHARDSON, UNITED STATES) |
| Trial ID | NIH-10653224 on ClinicalTrials.gov |
What this research studies
This research investigates how stimulating the right vagus nerve can affect the brain's reward systems that control appetite and food intake. By focusing on the differences between the left and right vagus nerves, the study aims to explore new methods for treating conditions related to eating behaviors and neurological disorders. Patients may receive electrical stimulation to the right cervical vagus nerve to see if it can help regulate their desire for food and improve their overall health. The research will involve understanding how this stimulation impacts the brain's reward circuits and appetite regulation.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals struggling with appetite control, eating disorders, or neurological conditions like epilepsy.
Not a fit: Patients who do not have issues with appetite regulation or those who are not affected by neurological disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for managing appetite and related neurological disorders.
How similar studies have performed: Previous research has shown promise in using vagus nerve stimulation for various neurological conditions, suggesting potential for success in this novel approach.
Where this research is happening
RICHARDSON, UNITED STATES
- UNIVERSITY OF TEXAS DALLAS — RICHARDSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: THORN, CATHERINE A — UNIVERSITY OF TEXAS DALLAS
- Study coordinator: THORN, CATHERINE A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disease