Using natural products to develop new treatments for cancer and infections
Pharmacophore - Directed Retrosynthesis Applied to Bioactive Natural Products Informing Mechanism of Action Studies
['FUNDING_OTHER'] · BAYLOR UNIVERSITY · NIH-11011281
This study is exploring how to create simpler versions of natural substances that could help fight cancer, infections, and immune system issues, with the goal of finding new treatments that work better and have fewer side effects for patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BAYLOR UNIVERSITY (nih funded) |
| Locations | 1 site (WACO, UNITED STATES) |
| Trial ID | NIH-11011281 on ClinicalTrials.gov |
What this research studies
This research focuses on the chemistry and biology of natural products that have potential anticancer, antibacterial, and immunosuppressive properties. By employing a method called pharmacophore-directed retrosynthesis, the researchers aim to design simplified versions of these natural products that retain their beneficial effects. This approach allows for the simultaneous study of the biological activity of these compounds while they are being synthesized, potentially leading to faster discoveries of effective treatments. Patients may benefit from new therapies that are derived from these natural products, which could be more effective or have fewer side effects.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with cancer or bacterial infections who may benefit from novel therapeutic agents derived from natural products.
Not a fit: Patients with conditions unrelated to cancer or bacterial infections may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new and more effective treatments for cancer and bacterial infections.
How similar studies have performed: Previous research has shown promise in using natural products for drug development, indicating that this approach could lead to significant advancements in treatment options.
Where this research is happening
WACO, UNITED STATES
- BAYLOR UNIVERSITY — WACO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROMO, DANIEL — BAYLOR UNIVERSITY
- Study coordinator: ROMO, DANIEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: anti-cancer