Using natural enzymes to create new drug compounds

Expanding the synthetic utility of enzymes

['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11163364

This project aims to develop new ways to use natural enzymes to create complex molecules that could become new medicines.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded)
Locations1 site (ANN ARBOR, UNITED STATES)
Trial IDNIH-11163364 on ClinicalTrials.gov

What this research studies

This project explores how to use natural enzymes to build complex molecules with high precision. Enzymes are excellent at making specific changes to molecules, which is crucial for developing new drugs and tools to understand biological systems. Researchers will discover new enzyme reactions and improve existing ones, making it easier to create molecules that could have powerful effects on health. The ultimate goal is to provide chemists with efficient and precise methods to make potential new treatments.

Who could benefit from this research

Good fit: This foundational chemistry research does not directly involve patients, but future clinical applications stemming from this work could benefit patients with a wide range of conditions requiring new therapeutic compounds.

Not a fit: Patients will not directly participate in or receive immediate benefit from this basic chemical synthesis research.

Why it matters

Potential benefit: If successful, this work could lead to the discovery and easier production of new drugs and chemical tools to treat various human diseases.

How similar studies have performed: Enzymes are already used in some industrial and pharmaceutical processes, but this project focuses on expanding their utility for creating novel and complex drug candidates.

Where this research is happening

ANN ARBOR, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.