Using nasal treatment with stem cell-derived particles to improve brain function in Alzheimer's disease
Intranasal Treatment of Stem Cell-derived Extracellular Vesicles for Alzheimer's Disease
This study is testing a new, gentle treatment for Alzheimer's that delivers helpful particles through the nose to improve brain function and mood, and it's designed for people with Alzheimer's at any stage of the disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m University Health Science Ctr NIH-funded |
| Lab location | 1 site (College Station, United States) |
| Project ID | NIH-10455945 on NIH RePORTER |
What this research studies
This research investigates a new, non-invasive treatment for Alzheimer's disease by administering therapeutic particles derived from human stem cells through the nose. The approach focuses on using these particles to deliver beneficial molecules directly to the brain, aiming to enhance brain function and reduce symptoms associated with Alzheimer's. The study will utilize mouse models to evaluate the effectiveness of this treatment in both early and advanced stages of the disease, assessing improvements in cognitive and mood functions. Preliminary findings suggest that this method may help reduce harmful brain changes and improve overall brain health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease, particularly in the early to advanced stages.
Not a fit: Patients with other forms of dementia or neurological disorders unrelated to Alzheimer's may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a novel treatment that significantly improves cognitive and emotional well-being for patients with Alzheimer's disease.
How similar studies have performed: Preliminary studies have shown promising results with similar approaches, indicating potential for success in this novel treatment strategy.
Where this research is happening
College Station, United States
- Texas A&m University Health Science Ctr — College Station, United States (Active)
Researchers
- Principal investigator: Shetty, Ashok K — Texas A&m University Health Science Ctr
- Study coordinator: Shetty, Ashok K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.