Using nasal bacteria to fight antibiotic-resistant infections
Nasal Microbial Consortia Combat Antibiotic-Resistant Bacteria
This study is looking at how helpful bacteria from the nose can be used to stop infections from tough germs like Staphylococcus and Streptococcus, especially for kids and adults who are more likely to get sick.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11049079 on NIH RePORTER |
What this research studies
This research aims to develop new therapies that use beneficial nasal bacteria to prevent infections caused by antibiotic-resistant bacteria like Staphylococcus aureus and Streptococcus pneumoniae. By cultivating human nasal bacteria on organoids, the researchers hope to block the colonization of these harmful bacteria in the nose, which is a common source of serious infections. The study focuses on understanding how to repopulate the nasal microbiome with protective bacteria to improve health outcomes, especially in children and adults who are at risk of these infections.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals, particularly children and adults, who are at risk of nasal colonization by antibiotic-resistant bacteria.
Not a fit: Patients who are not at risk of nasal infections or who do not carry antibiotic-resistant bacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that reduce the risk of serious infections without relying on antibiotics.
How similar studies have performed: Previous studies have shown promise in using beneficial bacteria to combat infections, suggesting that this approach could be effective.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Lemon, Katherine Paige — Baylor College of Medicine
- Study coordinator: Lemon, Katherine Paige
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.