Using nanoparticles to track T cells in cancer treatment
Nanoparticles to Track T Cell Immunotherapy Using Magnetic Particle Imaging
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-10772135
This study is exploring a new way to help T cell therapies work better for solid cancers by using a special imaging technique to see how T cells move and fight tumors, which could lead to safer and more effective treatments for patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10772135 on ClinicalTrials.gov |
What this research studies
This research focuses on improving T cell immunotherapy for solid cancers by using a novel imaging technique called magnetic particle imaging (MPI). It aims to non-invasively track the movement and effectiveness of T cells as they target tumors, while minimizing damage to healthy tissues. By developing superparamagnetic iron oxide nanoparticles, the study seeks to enhance the sensitivity of tracking T cells, allowing for better understanding of their behavior in the body. This could lead to improved treatment strategies and outcomes for patients undergoing T cell therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with solid tumors who are considering or undergoing T cell immunotherapy.
Not a fit: Patients with non-solid tumors or those not eligible for T cell immunotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer cancer treatments by providing real-time insights into T cell behavior during immunotherapy.
How similar studies have performed: Other studies have shown promise in using advanced imaging techniques for tracking immune cells, suggesting that this approach could be effective.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RINALDI-RAMOS, CARLOS M — UNIVERSITY OF FLORIDA
- Study coordinator: RINALDI-RAMOS, CARLOS M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer