Using nanoparticles to improve treatment for pancreatic cancer
Stroma penetrating and immune modulating nanoparticles for image-guided therapy of pancreatic cancer
This study is testing a new way to treat pancreatic cancer using tiny particles that can deliver medicine right to the tumor while also boosting the immune system, so patients might have a better chance at fighting their cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10874762 on NIH RePORTER |
What this research studies
This research focuses on developing a new approach to treat pancreatic cancer by using specially designed nanoparticles that can penetrate the dense tissue surrounding tumors. These nanoparticles are engineered to deliver cancer-fighting drugs directly to the tumor cells while also enhancing the immune response against the cancer. The study aims to combine these nanoparticles with immune checkpoint inhibitors to improve drug delivery and effectiveness. Patients may benefit from a more targeted and effective treatment option that overcomes the barriers that typically limit the success of current therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with pancreatic cancer who have not responded well to standard therapies.
Not a fit: Patients with early-stage pancreatic cancer or those who have not yet started treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for pancreatic cancer, improving survival rates and quality of life for patients.
How similar studies have performed: Other research has shown promise in using nanoparticles for targeted drug delivery in various cancers, indicating potential success for this novel approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Yang, Lily — Emory University
- Study coordinator: Yang, Lily
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.