Using nanoparticles to improve MR-guided radiation therapy for tumors
Translation of a Bismuth-Gadolinium Nanoparticle for MR-guided Radiation Therapy
This study is testing a new kind of tiny particle that could make radiation therapy for tumors more effective and safer, helping patients get better treatment with fewer side effects.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dana-Farber Cancer Inst NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10815534 on NIH RePORTER |
What this research studies
This research focuses on developing a new type of nanoparticle that enhances MR-guided radiation therapy, which is a cutting-edge treatment for various tumors. The project involves designing and rigorously testing bismuth-gadolinium nanoparticles to improve imaging and therapy outcomes. By conducting extensive evaluations of these nanoparticles in preclinical models, the research aims to ensure their safety and effectiveness in clinical settings. Patients may benefit from improved targeting of tumors with reduced side effects during radiation therapy.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with brain tumors or non-small cell lung cancer who are undergoing radiation therapy.
Not a fit: Patients with tumors that are not treatable with radiation therapy may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer radiation therapy options for patients with tumors.
How similar studies have performed: Previous studies have shown promising results with nanoparticle-enhanced radiation therapy, indicating potential for success in this novel approach.
Where this research is happening
Boston, United States
- Dana-Farber Cancer Inst — Boston, United States (Active)
Researchers
- Principal investigator: Berbeco, Ross I. — Dana-Farber Cancer Inst
- Study coordinator: Berbeco, Ross I.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.