Using nanoparticles to improve healing of chronic wounds in older adults
Protease Resistant Growth Factor Nanoparticles for Chronic Wound Healing
This study is looking at tiny particles that can help deliver healing substances to stubborn wounds, especially for older adults dealing with issues like diabetic foot ulcers and pressure sores, to make it easier for them to heal.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11301475 on NIH RePORTER |
What this research studies
This research focuses on developing nanoparticles that deliver growth factors to chronic wounds, particularly in older adults who are prone to conditions like diabetic foot ulcers and pressure ulcers. The approach aims to protect these growth factors from being degraded by proteases found in chronic wound environments, which often hinder effective treatment. By testing these nanoparticles in preclinical models, the research seeks to enhance the healing process and improve outcomes for patients suffering from difficult-to-treat wounds.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults suffering from chronic wounds such as venous leg ulcers, diabetic foot ulcers, or pressure ulcers.
Not a fit: Patients with acute wounds or those not experiencing chronic wound conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for chronic wounds, reducing the need for drastic surgical interventions.
How similar studies have performed: Previous research has shown promise in using growth factors for wound healing, but this approach with nanoparticles is innovative and aims to address specific challenges in translating these therapies to humans.
Where this research is happening
Tampa, United States
- University of South Florida — Tampa, United States (Active)
Researchers
- Principal investigator: Koria, Piyush — University of South Florida
- Study coordinator: Koria, Piyush
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.