Using nanoparticles to enhance CAR T cell therapy for breast cancer
Nanoparticle-augmented image-guided CAR T therapy and post-treatment assessment
This study is exploring a new way to make CAR T cell therapy for breast cancer even better by using tiny particles that help doctors see what's happening in the tumor, which could lead to more effective treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-10912062 on NIH RePORTER |
What this research studies
This research focuses on improving CAR T cell therapy for breast cancer by utilizing nanoparticles that enhance imaging techniques. The approach involves developing plasmonic nanoparticles that serve as contrast agents for ultrasound and photoacoustic imaging, allowing for better guidance during therapy. By monitoring the activity of CAR T cells in the tumor environment, the research aims to optimize treatment outcomes. Patients may benefit from more precise and effective cancer treatments through this innovative imaging technology.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with breast cancer who are considering CAR T cell therapy.
Not a fit: Patients with cancers other than breast cancer or those who are not eligible for CAR T cell therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted CAR T cell therapies for breast cancer patients.
How similar studies have performed: Other research has shown promise in using nanoparticles for imaging and therapy, indicating that this approach could be a significant advancement in cancer treatment.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Kim, Jinhwan — University of California at Davis
- Study coordinator: Kim, Jinhwan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.