Using nanomaterials to improve heart healing after a heart attack
Biomimetic nanomaterials for the immunomodulation of the cardiosplenic axis post-myocardial infarction
This study is looking at how special materials inspired by nature can help the immune system heal the heart after a heart attack, with the goal of finding new ways to improve recovery and reduce inflammation for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project ID | NIH-10981480 on NIH RePORTER |
What this research studies
This research investigates how biomimetic nanomaterials can modulate the immune response in the heart following a myocardial infarction (heart attack). It focuses on the role of monocytes and macrophages, which are immune cells that help heal the heart by removing damaged tissue and promoting repair. By understanding how these cells interact with the heart and the spleen during the healing process, the research aims to develop new strategies to enhance recovery and reduce inflammation. Patients may benefit from innovative treatments that improve heart function and healing after a heart attack.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently experienced a myocardial infarction.
Not a fit: Patients who have not had a heart attack or have chronic heart conditions unrelated to recent myocardial infarction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve heart recovery and reduce complications after a heart attack.
How similar studies have performed: Other research has shown promise in using biomimetic materials for immune modulation, indicating potential for success in this novel approach.
Where this research is happening
Charleston, United States
- Medical University of South Carolina — Charleston, United States (Active)
Researchers
- Principal investigator: Menick, Donald R. — Medical University of South Carolina
- Study coordinator: Menick, Donald R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.