Using nanohybrid materials to fight antibiotic-resistant infections in open fractures
Official title: Nanohybrid Composites Minimize Antibiotic Resistant Infections
Funded at West Virginia University · NIH-10882112 · Data updated 2026-11-12
This study is looking at new materials made from tiny silver particles and carbon tubes to help prevent infections in people with open fractures, especially those caused by tough bacteria that don't respond to regular antibiotics.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | West Virginia University NIH-funded |
| Lab location | 1 site (Morgantown, United States) |
| Project start | August 20, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $379,998 |
| NIH project number | 1R01AI177620-01A1 |
| Project ID | NIH-10882112 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have sustained open fractures and are at risk of developing infections.
✕Less likely to help
Patients with closed fractures or those who do not have a risk of infection may not benefit from this research.
What this research studies
This research focuses on developing innovative nanohybrid composites that combine silver nanoparticles and carbon nanotubes to combat infections associated with open fractures. Open fractures are prone to infections, particularly from antibiotic-resistant bacteria, which complicate treatment and recovery. The project aims to create materials that not only have strong antimicrobial properties but also minimize toxicity to the body. By testing these nanohybrids in laboratory settings, the researchers hope to find effective solutions for preventing and treating infections in patients with open fractures.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of infections in patients with open fractures, leading to better recovery outcomes and lower healthcare costs.
How similar studies have gone: Previous research has shown promise in using nanomaterials for antimicrobial applications, suggesting that this approach could be effective.
Where this research is happening
-
West Virginia University
Morgantown, United States Active
Researchers
- Principal investigator: Li, Bingyun — West Virginia University
- Study coordinator: Li, Bingyun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.