Using MRI to understand myofascial pain syndrome

MRI-based quantitative characterization of impaired myofascial interface properties in myofascial pain syndrome

NIH-funded research Mayo Clinic Rochester · NIH-10569208

This study is looking at myofascial pain syndrome, which causes muscle pain and stiffness, to create a new MRI method that can help doctors better understand what's happening in your muscles and tissues, so they can provide more accurate diagnoses and better treatments for you.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10569208 on NIH RePORTER

What this research studies

This research investigates myofascial pain syndrome (MPS), a common condition characterized by pain and stiffness in the muscles and connective tissues. The study aims to develop a non-invasive MRI-based technique to quantitatively assess the mechanical properties of myofascial tissues, which may help identify the underlying causes of pain. By creating new biomarkers, the research seeks to improve the understanding of how changes in these tissues contribute to MPS and evaluate the effectiveness of various treatments. Patients may benefit from more accurate diagnoses and targeted therapies based on the findings.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing chronic myofascial pain or related symptoms.

Not a fit: Patients with myofascial pain syndrome who are not experiencing significant symptoms or those with other underlying conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better diagnostic tools and treatment options for patients suffering from myofascial pain syndrome.

How similar studies have performed: Previous studies using ultrasound imaging have shown promise in understanding myofascial pain, but this MRI-based approach is relatively novel.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.