Using MRI to understand lung disease in premature infants
Official title: Physiologic phenotyping of chronic lung disease of prematurity using MRI
Funded at Weill Medical Coll of Cornell Univ · NIH-10997429 · Data updated 2026-11-12
This study is looking to create a new way to understand chronic lung disease in premature babies, specifically bronchopulmonary dysplasia, by using advanced MRI scans that don’t require any invasive procedures, so we can find better treatments for these little ones.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 10, 2023 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $376,577 |
| NIH project number | 5R01HL167003-02 |
| Project ID | NIH-10997429 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are premature infants diagnosed with chronic lung disease, particularly those with bronchopulmonary dysplasia.
✕Less likely to help
Patients who are not premature or do not have chronic lung disease may not benefit from this research.
What this research studies
This research aims to develop a new scoring system to better understand chronic lung disease, specifically bronchopulmonary dysplasia (BPD), in premature infants. By utilizing advanced MRI techniques, the study seeks to identify the underlying causes of BPD, such as issues with airways, lung structure, and blood flow, without the need for invasive procedures or sedation. The approach focuses on quantifying both lung function and structure, which could lead to more tailored treatments for affected infants. The research will involve assessing the contributions of different lung components to the disease, providing insights that could improve clinical care.
Why it matters
Potential benefit: If successful, this research could lead to more precise diagnoses and personalized treatment plans for premature infants suffering from chronic lung disease.
How similar studies have gone: Other research has shown promise in using MRI for lung imaging in pediatric populations, suggesting that this approach could be effective for understanding BPD.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Kovanlikaya, Arzu — Weill Medical Coll of Cornell Univ
- Study coordinator: Kovanlikaya, Arzu
Related research
Other NIH-funded projects on the same topics.
-
Butyrate-based approach to prevent vision loss in premature babies with retinopathy
A study is exploring whether increasing butyrate levels can prevent vision-damaging retinopathy in premature infants by addressing gut bacteria and metabolic pathways.
-
TopoROP: Multi-View Analysis to Diagnose Retinopathy of Prematurity
A new AI-based tool analyzes retinal images to help doctors diagnose Retinopathy of Prematurity in premature babies and other patients at risk.
-
Long-term endotypes of prematurity-related lung disease in former preemies
A long-term study looking at why some babies born very early develop lasting breathing problems and how their genes might explain these different paths.
-
Deep learning tool to diagnose retinopathy of prematurity in newborns
A new AI-based diagnostic tool uses eye images from premature babies to help clinicians identify treatment-needed retinopathy of prematurity.
-
Cortical dystonia in kids born early
Researchers are studying why premature birth leads to dystonia in cerebral palsy and looking for new ways to help children and adults who have this condition.
-
AI-enhanced wide-field eye scans for detecting retinopathy of prematurity
Using faster handheld wide-field eye scans plus AI to find early signs of retinopathy of prematurity in premature babies and help guide treatment.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.