Using MRI to study brain iron and protein buildup in Alzheimer's disease
Imaging brain iron and protein aggregation with MRI for assessing Alzheimer's disease pathology and progression
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA BERKELEY · NIH-11041016
This study is looking at how MRI scans can help us see and measure iron and protein buildup in the brains of people with Alzheimer's disease, with the goal of finding better ways to track how the disease progresses and improve diagnosis.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA BERKELEY (nih funded) |
| Locations | 1 site (BERKELEY, UNITED STATES) |
| Trial ID | NIH-11041016 on ClinicalTrials.gov |
What this research studies
This research investigates how MRI can be used to visualize and measure the buildup of iron and protein aggregates in the brains of individuals with Alzheimer's disease. The study aims to develop new biomarkers that can better predict the progression of the disease, as current methods have limitations in distinguishing between different types of brain changes. By focusing on the magnetic properties of these substances, researchers hope to improve understanding of Alzheimer's pathology and its impact on cognitive decline. Patients may undergo MRI scans to help identify these changes and contribute to the development of more effective diagnostic tools.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those at risk for developing the condition.
Not a fit: Patients with other forms of dementia or cognitive impairment unrelated to Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods for Alzheimer's disease, enabling earlier and more accurate detection of the condition.
How similar studies have performed: Previous research has shown promise in using MRI techniques to study brain changes in Alzheimer's, but this specific approach is novel and aims to address existing limitations.
Where this research is happening
BERKELEY, UNITED STATES
- UNIVERSITY OF CALIFORNIA BERKELEY — BERKELEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIU, CHUNLEI — UNIVERSITY OF CALIFORNIA BERKELEY
- Study coordinator: LIU, CHUNLEI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.