Using MRI to predict surgical outcomes in cervical spine injury
Official title: MRI-Derived Neuromuscular Signatures to Predict Surgical Response in Degenerative Cervical Myelopathy
Funded at Stanford University · NIH-11032875 · Data updated 2026-11-12
This study is looking at how degenerative cervical myelopathy affects your spinal cord and muscles, which can cause hand weakness and coordination problems, and it aims to use advanced MRI scans to help doctors figure out who might benefit from surgery to improve their condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | May 15, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $525,261 |
| NIH project number | 5R01NS128478-03 |
| Project ID | NIH-11032875 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with degenerative cervical myelopathy who are experiencing hand weakness and coordination difficulties.
✕Less likely to help
Patients with mild symptoms of degenerative cervical myelopathy or those who are not surgical candidates may not benefit from this research.
What this research studies
This research investigates how degenerative cervical myelopathy (DCM) affects the spinal cord and neuromuscular function, leading to hand weakness and coordination issues. By utilizing advanced MRI techniques, the study aims to create detailed neuromuscular profiles that reflect the health of the brain, spinal cord, and muscles. These profiles will help identify which patients are likely to benefit from surgical intervention, potentially improving surgical decision-making and outcomes for individuals with DCM.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions of surgical recovery for patients with degenerative cervical myelopathy.
How similar studies have gone: Previous research has shown promise in using imaging techniques to assess neuromuscular conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
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Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Weber, Kenneth Arnold — Stanford University
- Study coordinator: Weber, Kenneth Arnold
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.