Using MRI to measure blood flow in coronary arteries

Coronary Fractional Flow Reserve Determined Using MRI and CFD

NIH-funded research Emory University · NIH-10994598

This study is exploring a new, safer way to check blood flow in the heart using a special type of MRI, which could help people with heart issues without needing any invasive tests.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionEmory University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-10994598 on NIH RePORTER

What this research studies

This research investigates a new method to assess coronary fractional flow reserve (FFR) using non-invasive cardiac MRI combined with computational fluid dynamics. By measuring blood flow in the coronary arteries without the need for invasive procedures, this approach aims to provide a safer and more accessible way to evaluate patients with ischemic coronary artery disease. The study will involve developing and validating imaging techniques in healthy individuals before applying them to patients with stable coronary artery disease.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with stable ischemic coronary artery disease.

Not a fit: Patients with acute coronary syndromes or those who are not candidates for coronary interventions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment of coronary artery disease, reducing the need for invasive procedures.

How similar studies have performed: Previous research has shown promise in using non-invasive imaging techniques for assessing coronary blood flow, indicating potential success for this novel approach.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions atherosclerotic coronary disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.