Using MRI to improve treatment decisions for early breast cancer

MRI Radiomic Signatures of DCIS to Optimize Treatment

NIH-funded research University of Washington · NIH-10874568

This study is looking at how special MRI images can help doctors tell the difference between low-risk and high-risk cases of ductal carcinoma in situ (DCIS), the earliest stage of breast cancer, so that women can get the right treatment without going through unnecessary procedures.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10874568 on NIH RePORTER

What this research studies

This research investigates how MRI radiomic features can help optimize treatment for ductal carcinoma in situ (DCIS), the earliest form of breast cancer. By analyzing MRI images, the study aims to better distinguish between low-risk and high-risk cases of DCIS, which could reduce unnecessary treatments for many women. The approach focuses on understanding the biological characteristics of tumors and their surrounding environment, which are often missed by traditional imaging methods. This could lead to more personalized treatment plans and less anxiety for patients diagnosed with DCIS.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with ductal carcinoma in situ (DCIS) who are facing treatment decisions.

Not a fit: Patients with invasive breast cancer or those not diagnosed with DCIS may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce overtreatment and improve the quality of life for women diagnosed with DCIS.

How similar studies have performed: Previous research has shown promise in using imaging techniques to improve cancer treatment decisions, making this approach both innovative and grounded in prior successes.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.