Using MRI to improve diagnosis of heart failure with preserved ejection fraction
Cardiopulmonary Exercise MRI in Heart Failure with Preserved Ejection Fraction
This study is looking at a new way to diagnose heart failure with preserved ejection fraction (HFpEF) by using a special MRI while you exercise, to help better understand how your heart and lungs work when you're active, especially if you often feel short of breath during physical activity.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10917182 on NIH RePORTER |
What this research studies
This research investigates a new method for diagnosing heart failure with preserved ejection fraction (HFpEF) using cardiovascular MRI combined with exercise. Patients will undergo a non-invasive MRI while exercising on a special ergometer, allowing researchers to assess heart and lung function under stress. This approach aims to provide a more accurate diagnosis for patients who experience symptoms like breathlessness during physical activity, which can be difficult to diagnose with current methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients experiencing symptoms of heart failure, particularly those with preserved ejection fraction and difficulty in diagnosis.
Not a fit: Patients with advanced heart failure or those who do not experience symptoms related to heart function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely diagnoses of heart failure, improving treatment options and outcomes for patients.
How similar studies have performed: While the use of MRI in cardiovascular diagnostics is established, this specific approach combining exercise with MRI is relatively novel and has not been extensively tested.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Nezafat, Reza — Beth Israel Deaconess Medical Center
- Study coordinator: Nezafat, Reza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.