Using MRI to assess blood vessel health in aging and Alzheimer's patients
Clinically feasible functional MRI providing independent assessments of cerebrovascular stiffness and microcirculation in typical aging and Alzheimer's Disease cohorts
This study is looking at how the health of your blood vessels affects memory and thinking in people with Alzheimer's and those who are aging normally, using special MRI scans to gather important information that could help improve treatments for Alzheimer's.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project ID | NIH-10915451 on NIH RePORTER |
What this research studies
This research investigates how cerebrovascular health, specifically arterial stiffness and microcirculation, impacts Alzheimer's disease and typical aging. By utilizing advanced functional MRI techniques, the study aims to measure these vascular properties in large datasets from aging individuals and Alzheimer's patients. The goal is to better understand the relationship between vascular health and cognitive function, potentially leading to improved interventions for Alzheimer's disease. Patients will undergo MRI scans to gather data that could inform future treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults, particularly those showing early signs of cognitive impairment or diagnosed with Alzheimer's disease.
Not a fit: Patients with no cognitive impairment or those with other forms of dementia unrelated to Alzheimer's may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for Alzheimer's disease by highlighting the importance of vascular health.
How similar studies have performed: Previous research has shown promising results in using MRI techniques to assess vascular health, indicating that this approach could yield valuable insights into Alzheimer's disease.
Where this research is happening
West Lafayette, United States
- Purdue University — West Lafayette, United States (Active)
Researchers
- Principal investigator: Wright, Adam M — Purdue University
- Study coordinator: Wright, Adam M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.