Using MRI to analyze bladder function and anatomy in men with prostate issues
MR imaging-based Quantitative Analysis of Bladder Anatomy and Function in BPH/LUTS
['FUNDING_R01'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-10690752
This study is looking at how MRI scans can help us see changes in the bladder of men with benign prostatic hyperplasia (BPH) and urinary problems, so we can better understand how these issues affect their ability to urinate and find better treatments for them.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-10690752 on ClinicalTrials.gov |
What this research studies
This research investigates how MRI technology can be utilized to identify and measure changes in bladder structure and function in men suffering from benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). By comparing the bladder function of healthy young men to those with BPH/LUTS, the study aims to understand how diminished bladder contractility affects urine flow and emptying. The approach includes real-time imaging during voiding and computational modeling to assess bladder contraction metrics and urinary flow dynamics. This comprehensive analysis could lead to better treatment strategies for men experiencing these urinary issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are men diagnosed with benign prostatic hyperplasia and experiencing lower urinary tract symptoms.
Not a fit: Patients without benign prostatic hyperplasia or those with other unrelated urinary conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and treatment options for men with BPH/LUTS, enhancing their quality of life.
How similar studies have performed: Previous studies using MRI for bladder analysis have shown promising results, indicating that this approach is both innovative and grounded in successful methodologies.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROLDAN, ALEJANDRO — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: ROLDAN, ALEJANDRO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.