Using mouse models to improve treatment for idiopathic pulmonary fibrosis
Surfactant Protein C Mouse Models: A Fit For Purpose Preclinical Platform For Advancing Discovery In And Treatment Of Idiopathic Pulmonary Fibrosis
['FUNDING_U01'] · UNIVERSITY OF PENNSYLVANIA · NIH-10754510
This study is looking at a serious lung disease called idiopathic pulmonary fibrosis (IPF) in older adults by creating special mouse models to help us learn how certain gene changes affect the disease, with the hope of finding new treatments to help people with IPF feel better.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10754510 on ClinicalTrials.gov |
What this research studies
This research focuses on idiopathic pulmonary fibrosis (IPF), a serious lung disease affecting older adults, by developing advanced mouse models that mimic the disease. These models will help researchers understand how mutations in a specific gene related to lung function contribute to IPF and its progression. By studying these models, the research aims to identify new therapeutic strategies that could lead to better treatment options for patients suffering from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults diagnosed with idiopathic pulmonary fibrosis or those with a family history of the disease.
Not a fit: Patients with other forms of lung disease unrelated to idiopathic pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with idiopathic pulmonary fibrosis.
How similar studies have performed: Previous research has shown promise in using similar mouse models to advance understanding and treatment of lung diseases, indicating a potential for success in this approach.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BEERS, MICHAEL FRANCIS — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: BEERS, MICHAEL FRANCIS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.