Using MitoQ to improve blood flow in the brains of older adults
Official title: Chronic MitoQ Supplementation for Improving Cerebrovascular Function in Older Adults
Funded at University of Colorado · NIH-10998168 · Data updated 2026-11-12
This study is looking at how a special antioxidant called MitoQ might help improve blood flow and thinking skills in older adults by supporting brain blood vessel health.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Boulder, UNITED STATES) |
| Project start | September 1, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $42,030 |
| NIH project number | 1F31AG087709-01A1 |
| Project ID | NIH-10998168 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing cognitive decline or at risk for Alzheimer's disease and related dementias.
✕Less likely to help
Patients who are younger than 60 or do not have any cognitive decline or risk factors for Alzheimer's disease may not benefit from this research.
What this research studies
This research investigates the effects of a mitochondrial-targeted antioxidant called MitoQ on cerebrovascular function in older adults. The study aims to understand how MitoQ can enhance blood flow and cognitive function by addressing age-related declines in cerebrovascular health. Participants will be involved in an ongoing clinical trial that assesses the efficacy of MitoQ and its mechanisms of action. The research is led by a PhD student under the guidance of experienced faculty at the University of Colorado Boulder.
Why it matters
Potential benefit: If successful, this research could lead to improved brain health and cognitive function in older adults, potentially reducing the risk of Alzheimer's disease and related dementias.
How similar studies have gone: Previous research has shown promising results with antioxidants in improving cerebrovascular function, making this approach both relevant and potentially impactful.
Where this research is happening
-
University of Colorado
Boulder, United States Active
Researchers
- Principal investigator: Darvish, Sanna — University of Colorado
- Study coordinator: Darvish, Sanna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.