NIH-funded research NIH-funded research

Using mindfulness to improve treatment for opioid use disorder in those with childhood trauma

Official title: Improving Opioid Use Disorder Treatment Retention Outcomes Using Mindfulness in Childhood Trauma Survivors

Funded at University of Kentucky · NIH-11083044 · Data updated 2026-11-12

This study is looking at how mindfulness training delivered through technology can help people with opioid use disorder who have gone through childhood trauma, aiming to improve their emotional well-being and support their recovery journey.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Kentucky
NIH-funded
Lab location1 site (Lexington, United States)
Project startJune 15, 2023
Project endMay 31, 2028
Funding year2025
Award (this year)$187,804
NIH project number5K23DA054309-03
Project IDNIH-11083044 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with opioid use disorder who have experienced adverse childhood events.

Less likely to help

Patients who do not have a history of childhood trauma or who do not struggle with opioid use disorder may not benefit from this research.

What this research studies

This research focuses on developing mindfulness-based interventions to help individuals with opioid use disorder (OUD) who have experienced childhood trauma. The approach involves using technology to deliver mindfulness training, which aims to enhance emotional regulation and improve treatment retention. By studying the relationship between childhood trauma and treatment outcomes, the research seeks to identify biological markers that may indicate how trauma affects recovery. Participants will engage in mindfulness practices designed to support their recovery journey and improve their overall well-being.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment strategies for individuals with opioid use disorder who have a history of childhood trauma.

How similar studies have gone: Previous research has shown promise in using mindfulness interventions for addiction treatment, suggesting that this approach could be beneficial for the target population.

Where this research is happening

  • University of Kentucky
    Lexington, United States
    Active

Researchers

  • Principal investigator: Meadows, Amy Lynn — University of Kentucky
  • Study coordinator: Meadows, Amy Lynn

Related research

Other NIH-funded projects on the same topics.

  • Mindfulness-based help for people on methadone for opioid use

    A program tests an 8-week mindfulness-based therapy added to methadone treatment to help people with opioid use disorder reduce cravings, pain, and emotional distress.

    NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11392281

  • Mindfulness support added to methadone for opioid recovery

    This project adds an 8-week mindfulness and skills group to methadone care to help people with opioid use disorder reduce craving, pain, and emotional distress.

    NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11145083

  • Using mindfulness and mobile health to help treat opioid addiction

    This study is looking to help people with opioid use disorder by using mindfulness techniques and text messages to remind them about their medication and support them in managing cravings, making it easier for them to stick with their treatment.

    NIH research University of New Mexico · Albuquerque, United States · NIH-11055366

  • Using mindfulness techniques to improve methadone treatment for opioid addiction

    This study is looking at how a special 8-week group therapy called Mindfulness-Oriented Recovery Enhancement can help people with opioid use disorder who are in methadone treatment by teaching them skills to better handle pain and cravings, making their recovery journey easier and more successful.

    NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-10892925

  • Systems analysis to improve opioid use disorder care after jail release (SAIA-MOUD)

    A program to help people with opioid use disorder get better, faster, and safer care after they leave jail.

    NIH research University of Washington · Seattle, United States · NIH-11599161

  • Precise epigenetic drugs for opioid addiction

    A tiny, targeted drug approach is being developed to help people with opioid use disorder by rewriting the epigenetic signals in the brain to reduce cravings and relapse risk.

    NIH research Boston Interactome, INC. · Boston, United States · NIH-11578588

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.