Using microRNAs to improve diagnosis and prognosis in sarcoidosis
MicroRNA as Diagnostic and Prognostic Biomarkers in Sarcoidosis
This study is looking for tiny molecules in your lung fluid that could help doctors better diagnose and understand sarcoidosis, and if you choose to participate, your samples could help improve care for everyone with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11124898 on NIH RePORTER |
What this research studies
This research focuses on identifying specific microRNAs (miRNAs) that can serve as reliable diagnostic and prognostic biomarkers for sarcoidosis, a complex inflammatory disease. By analyzing bronchoalveolar lavage samples from patients, the study aims to validate previously identified miRNAs and assess their expression levels in relation to clinical characteristics. This genomic approach seeks to enhance the understanding of sarcoidosis and improve patient management through better diagnostics. Patients may be involved in providing samples and data to help validate these biomarkers.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with sarcoidosis, as well as healthy controls and patients with interstitial lung disease for comparison.
Not a fit: Patients with conditions unrelated to sarcoidosis or those who do not have access to the required diagnostic procedures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely diagnoses for patients with sarcoidosis, ultimately improving their treatment outcomes.
How similar studies have performed: Previous research has shown promise in using miRNAs as biomarkers in other diseases, suggesting potential success for this approach in sarcoidosis.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Lin, Nancy Weijiun — Johns Hopkins University
- Study coordinator: Lin, Nancy Weijiun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.