Using microRNAs to improve cancer treatment
Precision microRNA medicine in cancer
This study is looking at tiny molecules called microRNAs that can affect how cancer cells grow and spread, and it's for cancer patients who want to know more about new ways to diagnose and treat their condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10881765 on NIH RePORTER |
What this research studies
This research focuses on understanding how microRNAs (miRNAs) regulate cancer processes such as cell growth, survival, and spread. The team aims to identify specific miRNAs that are mis-expressed in various cancers and validate their roles using advanced laboratory techniques, including patient-derived organoid and animal models. By overcoming challenges in delivering these RNA-based therapies to cancer tissues, the research seeks to develop effective diagnostic and therapeutic strategies for cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include cancer patients who have specific miRNA mis-expressions related to their tumors.
Not a fit: Patients with cancers that do not involve the regulation of miRNAs or those who are not eligible for experimental therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, targeted treatments for cancer that improve patient outcomes.
How similar studies have performed: Previous research has shown promising results in using miRNA-based approaches for cancer treatment, indicating potential for success in this area.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Slack, Frank J. — Beth Israel Deaconess Medical Center
- Study coordinator: Slack, Frank J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.