Using microparticles to deliver anti-inflammatory treatments for spinal cord injury
Treating Spinal Cord Injury with Mineral Coated Microparticles Releasing Anti-Inflammatory Cytokines
This study is exploring a new way to help people with spinal cord injuries by using tiny particles that release special proteins to reduce inflammation, which can help heal the injury and encourage nerve growth.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-11054680 on NIH RePORTER |
What this research studies
This research investigates a novel approach to treat spinal cord injuries by using mineral-coated microparticles that release anti-inflammatory cytokines. The goal is to reduce excessive inflammation that can worsen neural damage following an injury. By delivering these cytokines locally at critical times, the treatment aims to improve healing and promote axon growth. Patients may benefit from a more effective and targeted therapy that addresses the inflammatory response associated with spinal cord injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently suffered a spinal cord injury and are experiencing significant inflammation.
Not a fit: Patients with chronic spinal cord injuries or those who do not exhibit an inflammatory response may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery outcomes for patients with spinal cord injuries.
How similar studies have performed: Previous research has shown promise in using localized delivery of anti-inflammatory agents, indicating potential success for this innovative approach.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Hanna, Amgad S — University of Wisconsin-Madison
- Study coordinator: Hanna, Amgad S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.