Using microfluidic technology to isolate cancer-fighting T-cells from blood
Official title: Microfluidic technology to isolate tumoricidal T-cells from peripheral blood
Funded at University of California at Davis · NIH-10896126 · Data updated 2026-11-12
This study is working on a new way to make cancer treatment better by using a special device to find and prepare the best T-cells from your blood to fight your specific cancer, so you can have a more effective and personalized therapy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $213,827 |
| NIH project number | 5R61CA278531-02 |
| Project ID | NIH-10896126 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are cancer patients who are undergoing or considering adoptive cell transfer therapy.
✕Less likely to help
Patients who do not have tumors or those whose cancers are not amenable to T-cell therapies may not benefit from this research.
What this research studies
This research focuses on improving adoptive cell transfer therapy, which uses a patient's own T-cells to fight cancer. The team aims to develop a microfluidic device that can efficiently separate tumoricidal T-cells from a larger population of blood cells. By exposing these T-cells to specific tumor antigens under controlled conditions, the researchers hope to enhance the effectiveness of this personalized treatment. This approach could lead to better outcomes for patients by ensuring that the T-cells used in therapy are specifically targeted to their tumors.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments for patients.
How similar studies have gone: Previous research has shown promise in using similar technologies for isolating specific T-cell populations, indicating potential for success in this approach.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Shirure, Venktesh — University of California at Davis
- Study coordinator: Shirure, Venktesh
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.